Current research studies

The CRASH-4 trial aims to provide reliable evidence about the effects of early intramuscular tranexamic acid on intracranial haemorrhage, disability, death and dementia in older adults with symptomatic mild head injury.

Study website: CRASH 4 Trial

Pilot Study findings: CRASH 4 Trial - Pilot Study

Patients with acute stroke symptoms being tested for large vessel occlusion (LVO) strokes using the LVOne lateral flow test https://upfrontdiagnostics.com/

Ambulance clinicians are providing feedback for the study research team on the usability of the tests in the pre-hospital setting.

The LVOne test uses finger-prick blood to help identify the presence of a large blood clot in the brain. A patient with a LVO stroke requires emergency surgery to remove the blood clot, also known as thrombectomy.

Early identification of LVO strokes by ambulance clinicians could offer opportunities for fast-tracking patients to thrombectomy-capable hospitals, avoiding delays to care when taken to other non-specialist hospitals.

Further information by this study can be found via https://emj.bmj.com/content/41/Suppl_3/A14.1

EEAST is collaborating with the University of Warwick, who are conducting a national research survey during to help learn about attending a child in cardiac arrest.

If you are an EEAST frontline ambulance clinician who is interested in taking part in this study, please email research@eastamb.nhs.uk for further information.