Current research studies

The CRASH-4 trial aims to provide reliable evidence about the effects of early intramuscular tranexamic acid on intracranial haemorrhage, disability, death and dementia in older adults with symptomatic mild head injury.

Study website: CRASH 4 Trial

Pilot Study findings: CRASH 4 Trial - Pilot Study

The University of Warwick is working with ambulance services to study how best to give people life-saving medications if their heart suddenly stops (they have a cardiac arrest). If your family member had a cardiac arrest and was treated by the East of England Ambulance Service, they may have been included in this study.

If you would like more information about this study, please contact the PARAMEDIC3 study team:

• Telephone: 024 765 72905
• Email: paramedic3@warwick.ac.uk
• Visit: www.warwick.ac.uk/paramedic3

Study protocol: PARAMEDIC3 - Protocol

Patients with acute stroke symptoms being tested for large vessel occlusion (LVO) strokes using the LVOne lateral flow test https://upfrontdiagnostics.com/

Ambulance clinicians are providing feedback for the study research team on the usability of the tests in the pre-hospital setting.

The LVOne test uses finger-prick blood to help identify the presence of a large blood clot in the brain. A patient with a LVO stroke requires emergency surgery to remove the blood clot, also known as thrombectomy.

Early identification of LVO strokes by ambulance clinicians could offer opportunities for fast-tracking patients to thrombectomy-capable hospitals, avoiding delays to care when taken to other non-specialist hospitals.

Further information by this study can be found via https://emj.bmj.com/content/41/Suppl_3/A14.1

EEAST is collaborating with the University of Warwick, who are conducting a national research survey during to help learn about attending a child in cardiac arrest.

If you are an EEAST frontline ambulance clinician who is interested in taking part in this study, please email research@eastamb.nhs.uk for further information.